Alternating electric fields therapy in oncology : a practical guide to clinical applications of tumor treating fields /

Alternating electric fields therapy in oncology : a practical guide to clinical applications of tumor treating fields /

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Bibliographic Details
Imprint:Switzerland : Springer, [2016]
©2016
Description:1 online resource
Language:English
Subject:
Electrotherapeutics.
Tumors -- Alternative treatment.
Oncology.
Glioblastoma -- therapy.
Electric Stimulation Therapy -- methods.
Electrotherapeutics.
Oncology.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11268161
Hidden Bibliographic Details
Other authors / contributors:Wong, Eric T., editor.
ISBN:9783319305769
331930576X
3319305743
9783319305745
Notes:Includes bibliographical references and index.
Print version record.
Summary:This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
Other form:Print version: Alternating electric fields therapy in oncology. [Place of publication not identified] : Springer, 2016 3319305743
Table of Contents:
  • 1. Cell Biological Effects of Alternating Electric Fields
  • 2. Fundamental Physics of Alternating Electric Fields Therapy
  • 3. Biophysical Effects of Alternating Electric Fields
  • 4. Computer Simulation of Alternating Electric Fields Therapy
  • 5. Response Pattern and Modeling of Tumor-Treating Fields
  • 6. Clinical Efficacy of Alternating Electric Fields for Recurrent Glioblastoma
  • 7. Alternating Electric Fields in Clinical Practice with Emphasis on PRiDe Registry
  • 8. Alternating Electric Fields Therapy for Newly Diagnosed Glioblastoma
  • 9. Supportive Care in Patients Using Alternating Electric Fields Therapy
  • 10. Future Directions for Alternating Electric Fields.

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